Du cannabis pour sauver le petit Sacha ?
Mai03

Du cannabis pour sauver le petit Sacha ?

À Saint-Germain-Laprade (Haute-Loire), le jeune Sacha Mallet souffre depuis sa naissance d’épilepsie partielle migrante. Une maladie infantile sur laquelle les médicaments n’ont pas d’effet… Compte tenu de l’évolution des connaissances scientifiques dans le domaine des cannabinoïdes, l’usage médical du cannabis redevient de plus en plus toléré, voire légal dans un nombre de pays : Canada, États-Unis, Autriche, Pays-Bas, Australie,...

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Molecular Targets of Cannabidiol in Neurological Disorders.
Mai03

Molecular Targets of Cannabidiol in Neurological Disorders.

Abstract Cannabis has a long history of anecdotal medicinal use and limited licensed medicinal use. Until recently, alleged clinical effects from anecdotal reports and the use of licensed cannabinoid medicines are most likely mediated by tetrahydrocannabinol by virtue of: 1) this cannabinoid being present in the most significant quantities in these preparations; and b) the proportion:potency relationship between tetrahydrocannabinol...

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Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders
Mai03

Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders

Abstract Objective To present a summary of current scientific evidence about the cannabinoid, cannabidiol (CBD) with regards to their relevance to epilepsy and other selected neuropsychiatric disorders. Methods We summarize the presentations from a conference in which invited participants reviewed relevant aspects of the physiology, mechanisms of action, pharmacology and data from studies with animal models and human subjects. Results...

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Analysis of endocannabinoid signaling elements and related proteins in lymphocytes of patients with Dravet syndrome
Mai03

Analysis of endocannabinoid signaling elements and related proteins in lymphocytes of patients with Dravet syndrome

Abstract Cannabidiol (CBD) reduces seizures in childhood epilepsy syndromes including Dravet syndrome (DS). A formulation of CBD has obtained orphan drug designation for these syndromes and clinical trials are currently underway. The mechanism responsible for CBD effects is not known, although it could involve targets sensitive to CBD in other neurological disorders. We believe of interest to investigate whether these potential...

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Medical Cannabis Bike Tour: Comment faire du vélo peut être radical
Mai03

Medical Cannabis Bike Tour: Comment faire du vélo peut être radical

De Reefer madness à l’image du stoner zonard bon à rien regardant la télévision, le cannabis a eu toutes sortes de mauvais stéréotypes. Pour cette raison, Paradise Seeds vous présente un événement qui mêle le cannabis et le sport avec des recherches médicales … et souffle ces stéréotypes paresseux au loin. En mai 2016, le Médical Cannabis Bike Tour roule encore avec l’objectif de financer des essais cliniques,...

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