Molecular Targets of Cannabidiol in Neurological Disorders.
Abstract Cannabis has a long history of anecdotal medicinal use and limited licensed medicinal use. Until recently, alleged clinical effects from anecdotal reports and the use of licensed cannabinoid medicines are most likely mediated by tetrahydrocannabinol by virtue of: 1) this cannabinoid being present in the most significant quantities in these preparations; and b) the proportion:potency relationship between tetrahydrocannabinol...
Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders
Abstract Objective To present a summary of current scientific evidence about the cannabinoid, cannabidiol (CBD) with regards to their relevance to epilepsy and other selected neuropsychiatric disorders. Methods We summarize the presentations from a conference in which invited participants reviewed relevant aspects of the physiology, mechanisms of action, pharmacology and data from studies with animal models and human subjects. Results...
How (and Why) Your Brain Makes Its Own Cannabinoids
As you probably already know, unlike water, potatoes, and many top-selling pharmaceutical drugs, it’s virtually impossible to fatally overdose on marijuana. What you might not realize, however, is that this remarkable attribute of weed stems from the fact that the human body actually produces its own « endogenous » cannabinoids (chemicals otherwise unique to the cannabis plant). These cannabinoids—whether formed in your brain or...
THC-A : Medical Benefits of THC Without the High
About THC-A: THC-A occurs when cannabigerol (CBG) is converted to THC-A , before being decarboxylated to THC in the trichome of the Cannabisflower. THC-A is non-psychoactive, acidic precursor of THC which alleviates: anxiety, depression, anorexia, pain, IBS/Crohn’s, spasticity, seizure (neuromuscular), nausea and much more without the psychoactivity of THC. Studies have even shown tumor suppression of some cancers with THC-A...
What is CBN and What are the Benefits of This Cannabinoid?
Do you remember the first time you heard about cannabidiol, or CBD? Remember how the national opinion of medical marijuana changed drastically once we gained knowledge of its non-psychoactive compounds? And who could forget how this discovery impacted the lives of children suffering from seizures and patients with chronic pain and inflammation? What you may not know is there are many other medicinal compounds like CBD unique to...
Principes actifs est une association qui a pour but de créer un réseau regroupant des personnes atteintes de maladies reconnues comme susceptibles de réagir favorablement à la prise de cannabis et en faisant usage.